In invasive breast cancer cells, enhanced AF1q expression induced pYSTAT3 levels through the Src kinase-driven platelet-derived growth factor beta (PDGFB)/platelet-derived growth factor receptor beta (PDGFRB) cascade, which was reversible upon Src kinase blockade with protein phosphate 1 (PP1) or PDGFRB blockade using imatinib [12]. Here, PDGFB is linked to invasive breast carcinoma.