These genes play important roles in cell proliferation (RFX4, FOXM1, ASF1B), differentiation during spermatogenesis (CATSPERG, SPDYA, SPATA16, TSACC, TCP10L, DPY19L2) and motility of sperm cells during fertilization (DNAAF1); mutations in these genes may lead to infertility. This evidence concerns the gene SPATA16 and Infertility.