ALB and neoplasm: By performing in vivo studies, in mice bearing 4T1 tumours, the authors observed a tumour uptake of HSA-Ce6/TAM NPs significantly higher than C-HSA-Ce6 NPs or Ce6 alone due to the pH-induced dissociation of HSA-Ce6/TAM NPs in HSA-Ce6 allowing an intratumoural penetration more efficient.