TNF and myocarditis: In 2012, Corsten et al. found that silencing of mir-155 by LNA-anti-miR in a mouse model of CVB3-induced myocarditis resulted in decreased T-cell activation; reduced numbers of intracardiac monocyte-macrophages; and decreased levels of TNF-α, IL-6, IL-10, and IFN-γ [23].