The successful targeting of the Warburg effect by the newly synthesized glucose derivatives is strongly suggested by the following findings: (a) correlation of cytotoxicity and selectivity of the synthesized conjugates with higher expression of GLUT-1 in human prostate cancer cells; (b) inhibition of cytotoxicity of the conjugates by addition of glucose to the media; c) ability of the compounds to inhibit a glucose uptake by cancer cells. Here, SLC2A1 is linked to Familial prostate cancer.