For example, NEv2 may be considered a tumor propagating cell (TPC, which encompasses the NE, or SCLC-A, subtype) by biomarkers in Jachan et al [24], yet expression of a single biomarker, HES1, would suggest this subtype falls outside of the NE subtype according to Lim et al [10]. The gene discussed is HES1; the disease is small cell lung carcinoma.