RDM1 and hepatocellular carcinoma: To reveal the biological role of RDM1 in HCC, RDM1 was either silenced using siRNAs in Bel‐7402 and SMMC‐7721 cells or overexpressed using a pcDNA3.1‐RDM1 plasmid in HepG2 and Bel‐7404 cells (Fig. 3A and Fig. S2A).