While NAT testing significantly improved transfusion safety, a case of the genotype 3 infection transmission by red cells concentrate (RBC) occurred in 2004.8 HCV RNA concentration in the infecting sample was below the analytical sensitivity of the screening performed at that time in minipools of 48 (estimated to be about 2000 IU/mL).8 However, decreasing the number of donations in each MP in subsequent years improved the analytical sensitivity to at least 40 IU/mL. Here, BRD2 is linked to infection.