FBP1 and non-small cell lung carcinoma: For example, the EMT-initiating transcription factor zinc finger E-box binding homeobox-1 (ZEB1) (the pathophysiological role of which is further reviewed in [182]) has been shown to directly upregulate the glucose transporter GLUT3, leading to increased glycolytic flux in NSCLC [183], and SNAI1 overexpression redirects carbons from glucose towards oxidative PPP by downregulating fructose-1,6-bisphosphatase (FBP1) expression in gastric cancer [184].