In an earlier study we described the correlation between high GLUT1 expression with poor differentiation grade and lymph node metastasis at diagnosis in adenocarcinomas in this same cohort of NSCLC patients.17 Also, we found a worse survival in adenocarcinomas with high GLUT1 and high MCT4 expression or high total lesion glycolysis (TLG) on 18F‐FDG‐PET/CT.17, 18 In this study, we further explored glucose metabolism‐related markers in adenocarcinoma subtypes. This evidence concerns the gene SLC2A1 and metastatic malignant neoplasm in the lymph nodes.