This co-staining showed localization of low phosphorylated STAT3 in LVs of healthy control mice from both genotypes and enhanced staining for phosphorylated STAT3 in cardiomyocytes and non-myocytes (distinguished by cell size and morphology) in WT mice with B16F10-TM, while in tumour diseased CKO mice only non-myocytes stained positive for phosphorylated STAT3 (Fig. 2E). Here, STAT3 is linked to neoplasm.