CASP3 and in situ carcinoma: Caspase 3/7 activity was significantly lower after treatment with EPA at 12.5 and 50 μM CIS (P = 0.011 and P = 0.034, respectively), with DPA at 12.5 until 100 μM CIS (P& 0.017) and with DHA at all CIS concentrations compared to control cells (P& 0.034, Figure 1F).