CDH6 and differentiated thyroid carcinoma: In TCGA clinical data on PTC patients (eBioPortal for Cancer Genomics https://www.cbioportal.org/) (Papillary thyroid carcinoma, Cell, 2014) [23], HOPX was positively correlated with CDH6 and LAMC2 that are involved in differentiation, while HOPX was negatively associated with HHEX and ERBB4 that contribute to dedifferentiation.