Also, HOPX was correlated with genes in a manner toward suppression of cancer cell progression; downregulation of TNRC6C, PAX8, TSHR, DYRK1A/B, and SLIT3 (pro-proliferation/migration), and upregulation of PCDH8/9, CDC42EP3/4/5, and TJP3 (anti-proliferation/migration) (Supplementary Figure 4 and Supplementary Table 2). The gene discussed is TSHR; the disease is cancer.