IL25 and asthma: Although additional experiments, like adoptive transfer of ILC2 from wild type and NIP45 deficient mice KO cells should be performed in RAG KO to study asthmatic phenotype by cytokine administration like IL-33 and/or IL25, targeting NIP45 emerges as a potentially novel approach for suppression of ILC2 cells and Th2 cytokine production in asthma.