The results showed the hMSH2 mRNA levels were significantly associated with OS when age, stage, grade, tumor size, and tumor residual size were included in the model (P = 0.03, HR = 1.91, 95%CI = 1.85–2.31, Table 3), but there was no obvious relationship between hMSH2 mRNA expression and PFS (P = 0.11, Table 3). This evidence concerns the gene MSH2 and neoplasm.