GSTZ1 and hepatocellular carcinoma: We evaluated the role of GSTZ1 in aerobic glycolysis in HCC cells on the basis of the oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) and assessed its effect on HCC proliferation, GSH concentration, ROS levels, and NRF2 signaling via gain and loss of GSTZ1 function in vitro.