Therefore, we wonder whether circWHSC1 can be secreted by ovarian cancer cells in the form of exosomes, taken up by peritoneal mesothelial cells, inducing up-regulation of MUC1 expression in mesothelial cells, and transformed into malignant mesothelial cells, which favors for peritoneal dissmination and tumor implantation. This evidence concerns the gene MUC1 and ovarian carcinoma.