DAVID analysis demonstrates ontological terms significantly associated with these genes to be “extracellular matrix,” “collagen,” “Ehlers-Danlos syndrome,” and “serpin.” Our GO::TermFinder results echo these findings; significant molecular functions of these genes were related to endopeptidase activity/regulation (SERPINA4, SERPINA3, SERPINA12, SERPINA9, SERPINA13P, SERPINA11, and SERPINA5) and ECM structural components (COL1A2, HAPLN1, VCAN, COL5A2, and COL3A1). This evidence concerns the gene VCAN and Ehlers-Danlos syndrome.