INS and fetal growth restriction: 2006). Although adrenergic dysregulation was shown to affect fetal islets with IUGR, daily administration of ADRβ modifiers did not improve islet response to glucose in IUGR lambs. However, there was a modest recovery in islet insulin content, which may reflect lower insulin demands due to the improved insulin sensitivity in IUGR‐AR lambs (Leos et al. 2010; Kelly et al. 2018).