TP53 and cancer: The importance of p53 in human cancer is evident given that the TP53 gene is mutated in about half of all sporadic cancers and in patients with Li‐Fraumeni syndrome, who are cancer prone (Li and Fraumeni, 1969) and harbor germline mutations in the TP53 gene (Freed‐Pastor and Prives, 2012; Manfredi, 2010).