In NB, a similar study was carried out with another inhibitor of Bcl-2, ABT-737, a mimetic molecule of proapoptotic BH3-only, which binds specifically Bcl-2, Bcl-xL and Bcl-w but has no affinity for Bcl-2-A1 and Mcl-1 [25]. The gene discussed is BCL2; the disease is neuroblastoma.