PCSK9 and hemorrhagic stroke: The point estimate for the GS association with hemorrhagic stroke (Fig. 2), OR 1.29 (95% CI 0.76, 2.19), was discordant to the estimate from PCSK9 inhibitor trials (OR 0.96 95% CI 0.75; 1.23) (Fig. 3), although the confidence intervals overlapped.