In the present study, there were no statistically significant differences in gender, age, HBsAg positivity, AFP positivity, histological grading and VGEF positivity in DPHCC or CK7- and CK19-negative HCC, but HBsAg positivity, AFP levels, and VGEF positivity were numerically lower in DPHCC, maybe suggesting that DPHCC is not as vascular as HCC. The gene discussed is KRT19; the disease is hepatocellular carcinoma.