In the present study, there were no statistically significant differences in gender, age, HBsAg positivity, AFP positivity, histological grading and VGEF positivity in DPHCC or CK7- and CK19-negative HCC, but HBsAg positivity, AFP levels, and VGEF positivity were numerically lower in DPHCC, maybe suggesting that DPHCC is not as vascular as HCC. This evidence concerns the gene KRT7 and hepatocellular carcinoma.