Further overlap with autism spectrum disorder (ASD, autism) database (https://gene.sfari.org/database/human-gene/) and ID database (http://www.ccgenomics.cn/IDGenetics/gene.php?dataset=IDGD_gene_detail) identified unique and shared mutated gene mutations (Tables S9–S11), with ADNP singled out as a gene associated with cytoskeleton/autism/ID/AD (Fig. 3a, b, Table S9). Here, ADNP is linked to Alzheimer disease.