SPRR2A and aneurysm: Moreover, two 12-LOX metabolites, i.e., 12-HETE (p = 0.032) and 14-HDoHE (p = 0.029), increased in the border area, and another 12-LOX metabolite, i.e., 12-HEPE (p = 0.042 for border and p = 0.038 for aneurysm), increased in both the border and normal areas.