To confirm the correlation between HSP47 and CRS, real-time PCR was performed using nasal tissues from each group (Control UP, n = 4; CRSsNP-UP, n = 10; CRSwNP-UP, n = 10; CRSwNP-NP, n = 13). This evidence concerns the gene SERPINH1 and chronic rhinosinusitis without nasal polyps.