To assess the presence of CD8+CXCR5+ T cells within HCC tumors, we used flow cytometry to analyze the CD8+CXCR5+ T cell content in 20 healthy blood samples and 40 HCC specimens (Table 1), each of which included blood, peritumoral liver, and tumor tissue samples the same patient. Here, CXCR5 is linked to neoplasm.