To evaluate the role of PDE4B polymorphism in panic disorder development we analyzed not only the substitutions rs10454453 (NM_002600.3:c.282-40611C>A, intron 6) and rs502958 (NM_002600.3:c.585-539A>T, intron 10) but also rs1040716 (NM_002600.3:c.635-20601A>T, intron 11), for which a correlation with schizophrenia was demonstrated [24]. Here, PDE4B is linked to schizophrenia.