The two lymphomas also showed peculiar features: PCTCL are rarely described in HIV<sup>+</sup> setting and particularly at such a low clinical stage, and the DLBCL showed uncommon cytology, non-GCB phenotype, EBER negativity, and absence of c-MYC translocation, all atypical features in this clinical context. This evidence concerns the gene MYC and diffuse large B-cell lymphoma.