Tian et al. [82] studied the in vivo anti-inflammatory activity of water extracts (Lm-a), total saponins (Lm-s), and main components (Lm-3) of Ophiopogon japonicus by establishing the inflammatory model of mice auricle-swelling and carrageenan- or histamine-induced swelling of the ankle of mice, and examined the in vitro anti-inflammatory activity of Lm-3 by tumor necrosis factor-α (TNF-α) or phorbol ester (PMA)-induced myeloid leukemia cell line (HL-60) and the human umbilical vein endothelial cell (ECV304) adhesion model. The gene discussed is TNF; the disease is myeloid leukemia.