In an experiment evaluating the biological effects of Lonicera japonica on a mouse model of chronic obstructive pulmonary disease, inhalation of Lonicera japonica microparticles reduced the levels of TNF-α and IL-6 in bronchoalveolar fluid of mice with chronic obstructive pulmonary disease and allowed them to be in peripheral blood. This evidence concerns the gene IL6 and chronic obstructive pulmonary disease.