Ginsenosides Ro could suppress autophagy by inhibiting autophagosome-lysosome fusion to sensitize esophageal cancer cells to 5-Fu-induced cell death [24] and inhibit the metastatic dissemination of colon cancer cells HT29 by suppressing the expression of p-ERK1/2 in HT29 cells [25]. The gene discussed is MAPK3; the disease is colonic neoplasm.