It has been recently demonstrated that N-cadherin expression is related to tumor growth, differentiation, growth size, nodes, and metastasis phase, proposing a possible role of N-cadherin in colorectal cancer progression, such as Su et al. [24] found that impedance with N-cadherin expression by a monoclonal immune response can viably delay the survival in an unconstrained exceptionally metastatic pancreatic cancer model [25]. The gene discussed is CDH2; the disease is colorectal cancer.