Alencar et al. showed that miR-181a was an independent prognostic factor in patients with DLBCL after standard R-CHOP chemotherapy; patients with low miR-181a expression had shortened progression-free survival (PFS), and high miR-181a expression inhibited FOXP-1 gene expression in the ABC-type of DLBCL [10]. The gene discussed is FOXP1; the disease is diffuse large B-cell lymphoma.