CD8A and ovarian serous tumor: In addition, Nielsen et al. found that, in high-grade serous ovarian tumors, CD20+ TIL colocated with activated CD8+ TIL and expressed antigen presentation markers, including MHC class I, MHC class II, CD40, CD80, and CD86, and the presence of both CD20+ and CD8+ TIL correlated with increased patient survival compared with CD8+ TIL alone [25].