We have reported that malignant ascites from ovarian cancer patients contained syncytium-like spheres as well as discrete cells that formed monolayers in culture, and that the material represented at least two types of potential TIC populations—one with Nanog/EpCAM, seen both in the spheres as well as in the monolayer-forming samples, and one with CD44/Oct-4A, found only in the latter [17]. Here, NANOG is linked to ovarian cancer.