Next, the mutant p53R273H-regulated miRNAs that were obtained from our sequencing study were validated in lung adenocarcinoma patients having wild-type or missense mutant p53 from the TCGA LUAD dataset (https://tcga-data.nci.nih.gov/docs/publications/luad_2014/). The gene discussed is TP53; the disease is lung adenocarcinoma.