In addition, the ROC curve based on the nine-TF pool also, respectively, showed an average 3, 5, and 10 year AUC for 0.721, 0.748, and 0.780 (Figure 8B), indicating that the nine-TF signature had very good prognosis effect and credibility for the survival of ccRCC patients. The gene discussed is TF; the disease is nonpapillary renal cell carcinoma.