A database search (NCBI, RGD) found no identified QTL for amylin production but the Chr 6 PDpLep peak in Leiter et al. (141.5 MB) co-located with coding and UTR SNP at amylin (islet amyloid polypeptide (Iapp)) (142.3 MB), a leptin agonist and insulin/glucagon regulator which forms pancreatic amyloid processes with cytotoxic effects on pancreatic β cells in T2DM [73]. Here, LEP is linked to type 2 diabetes mellitus.