PDCD1 and neoplasm: The combined treatment with anti-PD-1 + Pep R reduced the MC38 Relative Tumor Volume (RTV) by 2.67 fold as compared to untreated tumors (p = 0.038; 95% CI: 1374–5,44 RMANOVA with Tukey HSD post hoc-test) (Fig. 1a) while nor anti-PD-1, neither Pep R significantly impacted on tumor growth.