SLC12A3 and diabetic kidney disease: In this context, several epidemiological studies suggest that multiple genetic factors are involved in susceptibility of the pathogenesis of diabetic nephropathy, which has led to extensive research to identify the genes implicated in the development and progression of this condition [16, 23–25]; one of these genes is the solute carrier family 12 member 3 (SLC12A3) gene [16].