AKT1 and Sepsis: There is also evidence that the levels and activities of positive regulators of protein synthesis, such as insulin‐like growth factor 1 (IGF‐1), protein kinase B (AKT), and mammalian target of rapamycin complex 1 (mTORC1), diminish in skeletal muscles in response to sepsis (Lang et al., 2000; Lang et al., 2007; Stana et al., 2017).