When groups were considered separately, post‐ACTH serum cortisol and urine MT6s:creatinine ratio were not significantly correlated in dogs with PDH (r = .50, P = .08), in normal dogs (r = .13, P = .65) and dogs with SARDS (r = .03, P = .92). The gene discussed is POMC; the disease is pyruvate dehydrogenase deficiency.