CD8A and type 1 diabetes mellitus: However, when antigen‐specific and polyclonal CD8+ T cell populations were compared, PPI3–11‐ and InsB15–24‐specific CD8+ T cell populations in type 1 diabetes and control subjects contained significantly fewer naive cells and significantly more stem cell‐like memory, central memory and transitional memory cells compared to polyclonal CD8+ T cell populations (Fig. 2e,f).