CD8A and type 1 diabetes mellitus: However, some studies have reported higher frequencies of β cell‐reactive CD8+ T cells in HLA‐A*02+ or HLA‐A*24+ type 1 diabetes subjects compared to healthy donors 13, 89, 90, 91, and it is important to take into account differences in methods (such as dasatinib enhancement of tetramer staining) and study populations (i.e. adults versus children).