GDF5 and osteoarthritis: Enlightened by previous reports for the functional SNPs (rs143383 & rs143384, Figure 1C) of GDF5 in osteoarthritis, we carried out a replication study in Chinese population with 218 patients and 360 controls and achieved a significant signal (p= 0.02 for rs143384 and p=0.007 for rs143383, Figure 1C).