EGFR and neoplasm: This lipid insertion method has been further utilized by Zhang et al. and Chen et al. who decorated RBCm-cloaked PLGA nanoparticles with bispecific recombinant protein anti-EGFR-iRGD, containing both tumor-penetrating peptides (RGDs) and EGFR single-domain antibodies (sdAbs) to deliver antitumor drug gambogic acid (GA) and paclitaxel (PTX), respectively 73, 74.