It has been also shown that ABCB5 (ATP-binding cassette, sub-family B, member 5) contributes to WNT-dependent expression of CXCL8 (C-X-C motif chemokine ligand 8) encoding interleukin-8 to support a slow-cycling and chemoresistant phenotype of melanoma cells [69]. This evidence concerns the gene CXCL8 and melanoma.