The EBV-negative NPC cell lines 5-8Fand 6-10B were transiently transfected with the pcDNA3.1-LMP1 plasmid (a kind gift from Dr. Bi-Jun Huang from Cancer Center, SYSU) or an empty plasmid, and C666-1, an EBV-positive NPC cell line, was transfected with LMP1-specific siRNA. This evidence concerns the gene PDLIM7 and nasopharyngeal carcinoma.