DNAH17 and Reduced sperm motility: Further analyses of spermatozoa from patients and functional studies in mice carrying a Dnah17 mutation equivalent to that in patients collectively demonstrated that the DNAH17 variant specifically induces doublets 4–7 destabilization during sperm storage in epididymides and thus causes asthenozoospermia, signifying that DNAH17 is the first DNAH protein implicated in stabilizing flagellar structure.