miR-146a had antiviral properties against influenza infection [36], whilst it led to the regulation of ISG expression (including ISG16, ISG56, OAS1, and Mx1), enhanced viral replication in human cytomegalovirus-infected cells [37], and promoted the viral replication of Hendra virus and hepatitis C virus (HCV) [38,39]. Here, MX1 is linked to influenza.