C4B and hypertriglyceridemia: This contributes to an overproduction of TG-rich lipoprotein particles, including very-low-density lipoprotein (VLDL) cholesterol (VLDL-CH) and low-density lipoprotein cholesterol (LDL-CH), a decrease in high-density lipoprotein (HDL) cholesterol (HDL-CH) and hypertriglyceridemia [7].